A Caenorhabditis elegans Insulin-Like Peptide, INS-17: Its Physiological Function and Expression Pattern.

Autor: MATSUNAGA, Yohei, NAKAJIMA, Kensuke, GENGYO-ANDO, Keiko, MITANI, Shohei, IWASAKI, Takashi, KAWANO, Tsuyoshi
Předmět:
Zdroj: Bioscience, Biotechnology & Biochemistry; Nov2012, Vol. 76 Issue 11, p2168-2172, 5p
Abstrakt: The article discusses on determination of physiological function and expression of an insulin-like peptide, INS-17 in nematode Caenorhabditis elegans. It mentions that physiological function and expression of the peptide were analyzed by gene disruption and overexpression and results obtained were compared with that of INS-18. It was concluded that INS-17 regulates only larval diapause but not adult lifespan and functions as insulin receptor-like protein, DAF-2 antagonist.
Databáze: Complementary Index