Laparoscopic approach for the management of gastrointestinal stromal tumours (GIST) of the stomach.

Autor: Stathakis, P., Ayiomamitis, G., Tsigris, Ch.
Zdroj: Hellenic Journal of Surgery; Sep2012, Vol. 84 Issue 5, p296-302, 7p
Abstrakt: Aim-Background: The present review of the literature evaluates whether laparoscopic resection of gastric GISTs can become the new 'gold standard' treatment, analyzing perioperative characteristics and long-term oncological outcome. Surgery remains the standard treatment for non-metastatic gastrointestinal stromal tumours (GISTs). Laparoscopic surgery is considered a suitable option, since the biological behaviour of these tumours allows for curative resection without the necessity for large margins or extensive lymphadenectomies. Methods: A systematic review of gastrointestinal stromal tumours of the stomach treated by laparoscopy was conducted. Results: Up to 2008, laparoscopic surgery was attempted in 442 patients, of whom 254 were male and 188 female. Their average age was 61 years. The mean tumour size was 4.3 cm (1.0-7.5 cm); operative time ranged from 49-194.3 min, blood loss from 15-196ml, and hospital stay from 2.3 up to 12.2 days. All lesions had negative resection margins. The follow-up period for all patients ranged from 19 up to 61 months while the overall survival was 82%. Conclusions: The review of the literature concurred that laparoscopic resection is safe and effective in treating gastric GISTs. Taking into consideration the associated benefits of this minimally invasive approach, laparoscopic surgery should be considered in the surgical treatment of small- and medium-sized gastrointestinal stromal tumours of the stomach. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index