An environmentally benign protocol: catalyst-free Michael addition of aromatic amines to α,β-unsaturated ketones in glycerol.

Autor: Ying, Anguo, Zhang, Qunhui, Li, Hongmin, Shen, Gangfeng, Gong, Weizhong, He, Mingju
Předmět:
Zdroj: Research on Chemical Intermediates; Feb2013, Vol. 39 Issue 2, p517-525, 9p, 3 Charts
Abstrakt: Glycerol was used as a reaction medium as well as promoter for aza-Michael addition of aromatic amines to electronic deficient α,β-unsaturated ketones. Various aromatic amines can react smoothly with chalcone, 2-cyclohexen-1-one, 2-cyclopenten-1-one, and ethyl vinyl ketone to achieve good to excellent yields in the absence of any catalyst. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index