| Autor: |
Van Brandt, Sven, Rombouts, Frederik J. R., Martínez-Lamenca, Carolina, Leenaerts, Jos, Rauws, Tom R. M., Trabanco, Andrés A. |
| Zdroj: |
European Journal of Organic Chemistry; Dec2012, Vol. 2012 Issue 36, p7048-7052, 5p |
| Abstrakt: |
A simple and scalable procedure to introduce alcohols selectively at the 3-position of 3,4,5-trifluoroaniline is described. The procedure uses powdered NaOH as base and catalytic 15-crown-5 in refluxing toluene with a Dean-Stark trap. A short exploration of other nucleophiles and fluoroaryl electrophiles is also described. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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