Unsedated transnasal upper gastrointestinal endoscopy has favorable diagnostic effectiveness, cardiopulmonary safety, and patient satisfaction compared with conventional or sedated endoscopy.

Autor: Ai, Zheng-Lin, Lan, Chun-Hui, Fan, Li-Lin, Lan, Li, Cao, Yan, Li, Ping, Song, Ou, Chen, Dong-Feng
Předmět:
Zdroj: Surgical Endoscopy & Other Interventional Techniques; Dec2012, Vol. 26 Issue 12, p3565-3572, 8p, 1 Diagram, 3 Charts, 3 Graphs
Abstrakt: Background: To assess the diagnostic effectiveness, cardiopulmonary safety, and patient comfort of transnasal endoscopy (TNE), compared with conventional endoscopy (CES) and sedated endoscopy (SES), and to compare procedural risks and patient satisfaction/preference. Methods: In this prospective, randomized, and controlled protocol, eligible patients ( n = 397) in an outpatient clinic were randomized to CES ( n = 133), SES ( n = 134), or unsedated TNE ( n = 130) due to upper gastrointestinal (GI) complaints. Patients were continuously monitored for systolic/diastolic blood pressure (SBP/DBP), pulse rate (PR), and SpO throughout the endoscopy. All subjects ( n = 392) completing their assigned endoscopy were asked to evaluate endoscopy satisfaction, pain, and nausea/vomiting on visual analog scales. Patient preference for the assigned endoscopy was assessed against previous endoscopy experience or by willingness to repeat the assigned endoscopy. Results: Endoscopic outcomes for the esophagus, stomach, and duodenum were comparable among the three groups. SBP/DBP and PR were more stable in patients undergoing TNE than in those undergoing CES or SES, while SpO remained stable and above 95 % among all three groups. Patients were more satisfied with TNE than with CES and experienced less pain and nausea/vomiting. Patients exhibited a high preference for SES, whereas 67.6 % of patients who previously underwent SES and were randomly assigned to TNE were willing to undergo TNE again. Conclusions: TNE has comparable diagnostic effectiveness to CES and SES, but is less stressful on cardiopulmonary function, indicating that TNE is a more comfortable, preferred, and cost-effective endoscopic technique than CES and SES. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index