| Autor: |
Duynhoven, Y. T. H. P. van, Ossewaarde, J. M., Derksen-Nawrocki, R. P., Meijden, W. I. van der, Laar, M. J. W. van de |
| Zdroj: |
Clinical Infectious Diseases; 1998, Vol. 26 Issue 2, p314-322, 9p |
| Abstrakt: |
In 1994 Chlamydia trachomatis specimens from 175 men and 135 women attending a clinic for treatment of sexually transmitted disease were genotyped by polymerase chain reaction-based restriction fragment length polymorphism of the omp1 gene. Information about the patients was collected at their initial visit. The associations between C. trachomatis genotype and patients' selfreported symptoms, clinical signs, and characteristics were studied. Genotypes E, F, and D/Dpredominated (men: 71%; women: 60%). Five specimens (1.6%) showed evidence of mixed infections. Among men, complaints of urethral discharge and dysuria were most commonly associated with genotypes H and J (100% vs. 59%–68% for the other genotypes; P = .03); in addition, ⩾10 leukocytes per microscopic field were least often observed for genotypes G/Ga (19% vs. 59%–65% for the other genotypes; P = .01). Women's reports of lower abdominal pain were more often associated with F, G group genotypes (32%) than with B-complex (6%) or C-complex (13%) genotypes (P = .02). Certain symptoms of genital C. trachomatis infection were related to the infecting genotype. Further work will be necessary and should involve markers of the host immune response. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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