Multiple Liver Abscesses Due to Yersinia enterocolitica Discloses Primary Hemochromatosis: Three Case Reports and Review.

Autor: Vadillo, Miquel, Corbella, Xavier, Pac, Visitacion, Fernandez-Viladrich, Pedro, Pujol, Ramon
Zdroj: Clinical Infectious Diseases; 1994, Vol. 18 Issue 6, p938-941, 4p
Abstrakt: We report three cases of multiple liver abscesses due to Yersinia enterocolitica that led to previously unknown diagnoses of primary hemochromatosis. Y. enterocolitica is an iron-dependent bacterium that relies entirely on exogenous iron for growth. A review of the literature with use of MEDLINE (National Library of Medicine, Bethesda, MD) disclosed 35 cases of Y. enterocolitica liver abscesses; 21 (60%) of these cases were associated with hemochromatosis. In 11 of the remaining 14 cases, two common manifestations of hemochromatosis, diabetes mellitus and cirrhosis of the liver, also were present; these findings were significant. Finally, we emphasize that when iron overload cannot be documented at the time of diagnosis of the liver abscess, long-term follow-up for determination of increasing iron stores is mandatory. With this approach, most manifestations of hemochromatosis in asymptomatic patients can be prevented. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index