| Autor: |
Domingues, R. B., Muniz, M. R., Pinho, J. R. R., Bassit, L., Jorge, M. L. C., Saez Alquezar, A., Marchiori, P. E., Chamone, D. F., Scaff, M. |
| Zdroj: |
Clinical Infectious Diseases; 1995, Vol. 20 Issue 6, p1540-1542, 3p |
| Abstrakt: |
We conducted a prospective clinical and epidemiologic evaluation of 45 cases of human T lymphotropic virus type I (HTLV-1)—associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Sao Paulo, Brazil. All enrolled patients had progressive chronic myelopathy and high titers of HTLV-I and HTLV-II antibodies, as determined by enzyme immunoassay and western blot. In 24 cases, the polymerase chain reaction (PCR) was performed so that HTLV-I could be distinguished from HTLV-II. The clinical and epidemiologic features of the patients from our study were similar to those of patients with HAM/TSP from other areas of endemicity for HTLV-I except that more patients in our study had received a blood transfusion prior to their illness. Despite the presence of HTLV-II virus in Brazil, all patients whose serum was tested by PCR were found to be infected with the HTLV-I virus. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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