| Autor: |
RAJA GOPAL, P, CHANDRASHEKAR, E, SARAVANAN, M, VIJAYA BHASKAR, B, VEERA SOMAIAH, P |
| Předmět: |
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| Zdroj: |
Journal of Chemical Sciences; Sep2012, Vol. 124 Issue 5, p1077-1085, 9p |
| Abstrakt: |
A practical synthesis of (2-butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone, a key intermediate in the preparation of anti arrhythmic drug, is described. The commercially available 4-nitrophenol ( 3) is converted in five steps to 2-butyl-5-nitrobenzofuran ( 9) which upon Friedel-Crafts acylation with 4-methoxybenzoyl chloride followed by deprotection of methyl group gives ( 2). [Figure not available: see fulltext.] [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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