Development and Characterization of Curcumin Loaded Silver Nanoparticle Hydrogels for Antibacterial and Drug Delivery Applications.

Autor: Ravindra, Sakey, Mulaba-Bafubiandi, Antoine, Rajinikanth, V., Varaprasad, K., Narayana Reddy, N., Mohana Raju, K.
Předmět:
Zdroj: Journal of Inorganic & Organometallic Polymers & Materials; Nov2012, Vol. 22 Issue 6, p1254-1262, 9p
Abstrakt: The present work involves the development of curcumin loaded silver hydrogel nanocomposites based on acrylamide and 2-acrylamido-2-methyl propanesulfonic acid, as a template by redox co-polymerization in the presence of hydrophilic crosslinker N, N-methylenebisacrylamide. Silver nitrate was taken as the metal precursor and sodium borohydride as a reducing agent. The formation of silver nanoparticles was monitored using UV-Vis absorption spectroscopy. The developed hydrogel silver nanocomposites (HSNC) were characterized by FTIR, UV-Vis, thermogravimetric analysis, scanning electron microscopy and transmission electron microscopy. The curcumin loading and release characteristics were performed for different hydrogel systems. The developed HSNCs were evaluated for preliminary antibacterial applications. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index