| Autor: |
Struijk, D. G., Bakker, J. C., Krediet, R. T., Koomen, G. C. M., Stekkinger, P., Arisz, L. |
| Zdroj: |
Nephrology Dialysis Transplantation; 1991, Vol. 6 Issue 3, p198-202, 5p |
| Abstrakt: |
The effects of intraperitoneal administration of two different batches of human albumin (batch A and batch B) on peritoneal solute transport and dialysate white cell count were studied in 16 CAPD patients. The studies were done on two separate days during a 4-h dwell, one day without and one day with the intraperitoneal administration of 10 g/l human albumin. Marked differences were found between the two batches. The transport of all measured solutes increased during administration of batch A compared to the control experiments: urea 78% ± 62%, lactate 51% ± 38%, creatinine 96% ± 54%, glucose 67% ± 55%, inulin 27% ± 33% IgG 126% ± 80%, mean ± SD; P<0.02).In the experiments with batch A the white cell count of the test bag was greater than that of the effluent (‘night bag’) before the test (13 ± 5 vs 194 ± 61 mm3/l; P<0.02). These effects were also observed when the dialysate was buffered to pH = 7.4 before inflow. Albumin batch B showed no effect on solute transport and white cell count.The effects on solute transport and white cell count are probably caused by the greater concentration of prekallikrein activator in batch A when compared to batch B (30.1 vs 0 U
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| Databáze: |
Complementary Index |
| Externí odkaz: |
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