| Autor: |
GILES, R. W., EIKENS, E., PAOLONI, H. J., GLOVER, W. E., WILCKEN, D. E. L. |
| Zdroj: |
Cardiovascular Research; Nov1975, Vol. 9 Issue 6, p779-787, 9p |
| Abstrakt: |
Intracoronary administration of isoprenaline, adrenaline, and noradrenaline in the Langendorff-type transplanted dog heart transiently decreased coronary blood flow measured from the inflow vessel; flow then increased. The reduction in coronary flow coincided with increased myocardial contractility and was prevented by keeping the left ventricle empty. Propranolol prevented changes in flow and contractility. It is concluded that positive inotropic changes result in the ejection of accumulated Thebesian flow from the ventricle and affect coronary flow measurements and that the interpretation of flow changes requires a steady state. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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