| Autor: |
Quaglione, Raffaele, Calcagnini, Giovanni, Censi, Federica, Malavasi, Mario, Raveggi, Marco, Biancalana, Gianluca, Bartolini, Pietro, Critelli, Giuseppe |
| Zdroj: |
EP: Europace; 2005, Vol. 7 Issue 4, p366-373, 8p |
| Abstrakt: |
Aims The aims of the study were to evaluate the 24-h beat-to-beat heart rate (RR) and blood pressure changes during closed loop stimulation (DDD-CLS) pacing and conventional fixed rate DDD pacing with respect to spontaneous activity. Methods We simultaneously and continuously measured beat-to-beat heart rate and blood pressure for 24 h in patients implanted with Inos2+ (Biotronik GmbH, Berlin, Germany). A randomised cross-over comparison of DDD-CLS and DDD pacing was performed by short- and long-term analyses. Results Seventeen patients (10 males, aged 46–85 years) were enroled in the study: 11 completed the protocol. The percentage of atrial stimulation was 72.87% during DDD-CLS and 38.36% in DDD (P = 0.003). All patients were 100% stimulated in the ventricle. On average, the percentage increase of paced RR intervals with respect to spontaneous beats was only 7.4% in DDD-CLS but 20.1% in DDD (P = 0.0001). A significant correlation between spontaneous and paced RR profiles was obtained only during DDD-CLS (rDDD-CLS = 0.77, rDDD = 0.23, P = 0.01). Short-term analysis revealed a 3.79% reduction of the escape interval in DDD-CLS and 8.19% in DDD, and the relative fall in diastolic blood pressure was 1.14% in DDD-CLS and 3.81% in DDD. Conclusion DDD-CLS provided physiological heart rate fluctuations throughout the 24-h test. The blood pressure profiles of paced and spontaneous beats were comparable. The onset of paced rhythm in DDD-CLS resulted in a less pronounced decrease in heart rate and fall in diastolic pressure than in DDD. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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