| Autor: |
Bret, L., Chanal, C., Sirot, D., Labia, R., Sirot, J. |
| Zdroj: |
Journal of Antimicrobial Chemotherapy (JAC); 1996, Vol. 38 Issue 2, p183-191, 9p |
| Abstrakt: |
Ten clincial isolates of Proteus mirabilis were found to produce an inhibitor-resistant TEM β-lactamase (IRT) in association with a TEM-1 enzyme. The IRT enzyme was derived from TEM-2. The blaIRT gene differs from blaTEM-2 gene by one point mutation which leads to the amino-acid substitution Arg→Ser at position 244, as observed for the original IRT-2 enzyme derived from TEM-1 reported in Escherichia coli. This is the first report of an IRT β-lactamase derived from TEM-2. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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