Partial restoration of cAMP-stimulated CFTR chloride...

Autor: Jiang, Canwen, Fang, Shaona L., Yong-Fu Xiao, O'Connor, Sean P., Nadler, Steven G., Lee, Des W., Jefferson, Douglas M., Kaplan, Johanne M., Smith, Alan E., Seng H. Cheng
Předmět:
Zdroj: American Journal of Physiology: Cell Physiology; Jul98, Vol. 275 Issue 1, pC171, 8p, 1 Black and White Photograph, 4 Graphs
Abstrakt: Provides information on a study which examined the ability of deoxyspergualin (DSG) to promote trafficking of ...F508-cystic fibrosis transmembrane conductance regulator (CFTR) to the cell membrane. Materials and methods; Effect of DSG on immortalized cystic fibrosis (CF) epithelial cells; Therapeutic approaches for the treatment of CF; Conclusions.
Databáze: Complementary Index