| Autor: |
Phair, John P., Margolick, Joseph B., Jacobson, Lisa P., Phillips, Jack, Rinaldo, Charles, Kaslow, Richard, Chu, Clara, Giorgi, Janis V., Henrard, Denis |
| Zdroj: |
Journal of Infectious Diseases; 1997, Vol. 175 Issue 4, p959-962, 4p |
| Abstrakt: |
Early (pre-seroconversion) infection with human immunodeficiency virus type 1 (HIV-1) was identified in 50 of 267 participants in the Multicenter AIDS Cohort Study. These 50 men had a positive EIA result, which detected IgM antibody (n = 35), p24 antigen, or serum HIV RNA (n = 15) at their last “seronegative” visit. At that visit, the mean CD4 lymphocyte number (890/mm3 vs. 1038/mm3) was significantly lower than in men who subsequently seroconverted but had no evidence of early infection. The decline in CD4 cells was slower and the duration of AIDS-free time longer in the 19 men who were symptomatic in comparison to the 31 asymptomatic men with early infection, but differences were not significant. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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