| Autor: |
Boyer, Nathalie, Marcellin, Patrick, Degott, Claude, Degos, Francoise, Saimot, Adrien Gérard, Erlinger, Serge, Benhamou, Jean Pierre |
| Zdroj: |
Journal of Infectious Diseases; 1992, Vol. 165 Issue 4, p723-726, 4p |
| Abstrakt: |
To assess the response to and tolerance of recombinant interferon-α administration in patients with chronic hepatitis C and human immunodeficiency virus (HIV) infection, 12 patients with chronic hepatitis C and HIV infection were given interferon-α, 1, 3, or 5 million units thrice weekly, for 4 or 6 months. Four patients had a complete response (normal serum alanine aminotransferase activity [ALT]), 3 had a near-complete response (serum ALT less than one-and-onehalf times the upper limit of normal), and 5 had no response at the end of administration. Histologic examination of liver showed an improvement in 1 patient with complete response and no improvement in another patient with no response. In patients with chronic hepatitis C with HIV infection, the response to and tolerance of recombinant interferon-a were not different from those usually observed in patients with chronic hepatitis C infection without HIV infection. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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