| Autor: |
Anderson-Visoná, Kirsten, Villarejos, Victor M. |
| Zdroj: |
Journal of Infectious Diseases; 1980, Vol. 141 Issue 5, p603-608, 6p |
| Abstrakt: |
Chronic carriers of hepatitis B surface antigen (HBsAg) who were positive for antibody to hepatitis B e antigen were tested for precipitating specificities of the antibody and for rheumatoid factor (RF) over a two-year period. Twenty-one of 69 carriers were RFpositive by the latex-RF test with human IgG, but all were negative by the hemagglutination- RF test with rabbit IgG. Antibody to e/1 antigen was identified as an IgM antibody reactive in the latex-Rf test, whereas antibody to e/2 antigen belonged to the IgG class and showed no RF reactivity. Antibody production seems to follow a sequential evolution: antibody to e/1 antigen appears early and that to e/2 antigen follows shortly thereafter. Antibody to e/2 antigen remains as the permanent antibody, whereas that to ell antigen sometimes disappears. The fact that antibody to e/1 antigen is present only in certain chronic carriers of HBsAg would account for discrepancies in reported results of RF tests in viral hepatitis. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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