| Autor: |
Sada D., Eduardo, Ferguson, Lavenia E., Daniel, Thomas M. |
| Zdroj: |
Journal of Infectious Diseases; 1990, Vol. 162 Issue 4, p928-931, 4p |
| Abstrakt: |
An ELISA was established for the measurement of IgG antibody in human serum to the 30,000-Da native antigen of Mycobacterium tuberculosis and evaluated for its utility in the diagnosis of tuberculosis at the Instituto Nacional de Enfermedades Respiratorias in Mexico City. The test had a sensitivity of 70% in patients with sputum-positive active pulmonary tuberculosis and a specificity in control subjects of 100%. The accuracy ofpositive prediction was100% and of negative prediction 93% for patients with pulmonary tuberculosis at this institute. Less favorable test characteristics were obtained for patients with miliary and pleural tuberculosis, in which the test had sensitivities of 22% and 14%. These results offer the promise ofan accurate serodiagnostic test for pulmonary tuberculosis using readily obtained reagents. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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