| Autor: |
Baldassarri, Marta, Bonfante, Estevam, Suzuki, Marcelo, Marin, Charles, Granato, Rodrigo, Tovar, Nick, Coelho, Paulo G. |
| Zdroj: |
Journal of Biomedical Materials Research, Part B: Applied Biomaterials; Oct2012, Vol. 100B Issue 7, p2015-2021, 7p |
| Abstrakt: |
Bone remodeling, along with tissue biomechanics, is critical for the clinical success of endosseous implants. This study evaluated the long-term evolution of the elastic modulus (GPa) and hardness (GPa) of cortical bone around human retrieved plateau root form implants. Thirty implant-in-bone specimens showing no clinical failure were retrieved from patients at different in-vivo times (0.3 to ∼24 years) due to retreatment needs. After dehydration, specimens were embedded in methacrylate-based resin, sectioned along the bucco-lingual long axis and fixed to acrylic plates and nondecalcified processed to slides with ∼50 μm in thickness. Nanoindentation testing was carried out under wet conditions on bone areas within the first three plateaus. Indentations ( n = 120 per implant total) were performed with a maximum load of 300 μ N (loading rate: 60 μ N/s) followed by a holding and unloading time of 10 s and 2 s, respectively. Elastic modulus (E, GPa) and hardness (H, GPa) were computed. Both E and H values presented increased values as time in vivo elapsed (E: r = 0.84; H: r = 0.78). Significantly higher values for E and H were found after 5 years in vivo ( p < 0.001). Maxillary or mandibulary arches or positioning did not affect mechanical properties, nor did implant surface treatment on the long-term bone biomechanical response (E: p ≥ 0.09; H: p ≥ 0.3). This work suggests that human cortical bone around plateau root form implants presents an increase in elastic modulus and hardness during the first 5 years following implantation and presents stable mechanical properties thereafter. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2012. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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