Using aptamers evolved from cell-SELEX to engineer a molecular delivery platform.

Autor: Mallikaratchy, Prabodhika, Haipeng Liu, Yu Fen Huang, Hui Wang, Lopez-Colon, Dalia, Weihong Tan
Předmět:
Zdroj: Chemical Communications; 6/7/2009, Issue 21, p3056-3058, 3p
Abstrakt: We report a chemically modified construct of the Sgc8 aptamer, selected against CEM cells, conjugated to an activator platform for stimulated release of molecules at the tumor surface using DNA template assisted functional group transfer reactions (DTGTR). [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index