| Autor: |
De Lapiscina, Elena Hernández Martínez, Aguirre, María Elena Erro, Blanco, Teresa Ayuso, Pascual, Ivonne Jericó |
| Zdroj: |
Muscle & Nerve; Aug2012, Vol. 46 Issue 2, p174-180, 7p |
| Abstrakt: |
Introduction: There is much research on quality of life in myasthenia gravis (MG), and its relationship to disease severity is well-established. However, evidence regarding sleep disturbance in MG is inconclusive. Methods: To evaluate sleep and quality of life among clinically stable MG patients, 54 subjects were investigated by means of the Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS) and 15-Item-Quality-Of-Life Instrument for MG (MG-QOL15). Results: A pathological PSQI score, which was observed in 59% of patients, was increased in subjects with active disease compared with patients in clinical remission [odds ratio = 4.3; confidence interval 95% (1.0-17.6); P = 0.04]. We found a relationship between PSQI and MG-QOL15 scores in patients with clinically active disease (r = 0.62; P < 0.001). Conclusions: Our study highlights the high prevalence of sleep disturbance among MG patients. Disease severity may be considered to be a MG-specific risk factor for patient-reported sleep disturbance. The MG-QOL15 and PSQI should be used to estimate the impact of the disease on sleep and quality of life. Muscle Nerve 46: 174-180, 2012 [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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