A QUANTITATIVE EVALUATION OF EPITHELIUM AND INFLAMMATORY INFILTRATE OF LICHEN PLANUS AND LICHENOID REACTIONS.

Autor: Balan, Usha, Gonsalves, Nitin, Jose, Maji
Předmět:
Zdroj: Oral & Maxillofacial Pathology Journal; Jul-Dec2012, Vol. 3 Issue 2, p233-237, 5p, 4 Color Photographs, 1 Chart, 2 Graphs
Abstrakt: Lichen planus and Lichenoid reaction are two different entities that pose a diagnostic dilemma. Objectives: Lichen planus and Lichenoid reactions are clinically and histopathologically very similar but have different treatment and prognosis. This particular study is aimed at differentiating both these entities histopathologically with the use of micrometry and to find the role of subepithelial chronic inflammatory infiltrate on overlying epithelium with regard to its thickness. Methods: In the present study, Lichen Planus (n=30) and Lichenoid reactions (n=10) were studied. Using eyepiece graticule, epithelial thickness and subepithelial inflammatory band thickness were measured in these lesions. Results: Positive correlation was seen between epithelial and inflammatory band thickness in cases of lichenoid reactions and a negative correlation in cases of lichen planus. Conclusion: The study suggests that the nature and thickness of subepithelial infiltrate has an influence on the overlying epithelium in Lichen Planus and Lichenoid reaction. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index