SYNTHESES OF NOVEL SUBSTITUTED-BORANOPHOSPHATE NUCLEOSIDES.

Autor: Vyakaranam, Kamesh, Rana, Geeta, Spielvogel, BernardF., Maguire, JohnA., Hosmane, NarayanS.
Předmět:
Zdroj: Nucleosides, Nucleotides & Nucleic Acids; Aug2002, Vol. 21 Issue 8/9, p581-598, 18p
Abstrakt: A number of substituted (borano) nucleic acids, 3′-[diethylphosphite-(cyano, carboxy, or carbamoyl) borano] deoxynucleosides (3a–4c) and 5′-[diethylphosphite(cyano or carboxy) borano] deoxynucleosides (6a–7d) were prepared by a variety of synthetic procedures. The syntheses of the pyrophosphates (2a–2c), as precursors for 3a–4c, are also described. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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