Intraocular Lymphoma: Current Therapy and Future Trends.

Autor: Calvano, Christopher J., Kim, Stella K., Gombos, Dan S.
Zdroj: Ophthalmic Oncology; 2011, p485-489, 5p
Abstrakt: Intraocular lymphoma is a rare non-Hodgkin΄s lymphoma with three main presentations: primary retinal lymphoma, primary uveal lymphoma, and secondary uveal lymphoma in a patient with known central nervous system lymphoma. Primary intraocular lymphomas are usually diffuse large B-cell lymphomas and generally are associated with a poor prognosis. Patients present with recurrent vitritis or uveitis that may initially respond to topical steroids. Some complain of increased floaters or generalized blurry vision. Cytologic evaluation is the mainstay of accurate diagnosis of primary intraocular lymphoma; genetic information from flow cytometry evaluation may also be useful. There is no clear consensus on treatment, but generally whole-eye radiotherapy should be considered, possibly after administration of systemic high-dose methotrexate. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index