| Autor: |
Brunner, Stefanie, Holub, Ines, Theis, Stephan, Gostner, Andrea, Melcher, Ralph, Wolf, Petra, Amann-Gassner, Ulrike, Scheppach, Wolfgang, Hauner, Hans |
| Předmět: |
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| Zdroj: |
Diabetes Care; Jun2012, Vol. 35 Issue 6, p1249-12, 3p, 1 Chart |
| Abstrakt: |
OBJECTIVE - To test the hypothesis that replacement of sucrose with isomaltulose in sweet foods and beverages improves metabolic control in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS - One hundred ten patients with type 2 diabetes were randomized to receive sweet foods containing either 50 g/day isomaltulose or sucrose for 12 weeks as part of their habitual diet under free-living conditions. HbA1c at 12 weeks was the primary outcome parameter. RESULTS - In the final analysis comprising 101 patients, isomaltulose did not significantly affect HbA1c at 12weeks (sucrose: 7.3960.78%; isomaltulose: 7.2460.76%; regression coefficient [b]: 0.02 [95%CI:-0.21 to 0.25], P = 0.844). Triglycerides at 12 weeks were significantly lower in the isomaltulose versus the sucrose group (b: 34.01 [6.59-61.44], P =0.016).Othersecondary parameters did not significantly differ between groups. CONCLUSIONS - Isomaltulose did not influence glycemic control assessed as HbA1c in type 2 diabetes under free-living conditions but was associated with lower triglyceride levels. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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