| Autor: |
Klar, Uirich, Platek, Johannes |
| Předmět: |
|
| Zdroj: |
Synlett; Jun2012, Vol. 23, p1291-1299, 9p |
| Abstrakt: |
We describe our successful efforts for the translation of our research strategy that was focused on a broad structural modification of the natural product epothilone B, to the production of the distinct drug candidate sagopilone in a kg scale. By a direct comparison of the research and development procedures we address some important aspects to be considered for an up-scaling process. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
