Targeting cathepsins: a new glimmer of hope for pancreatic cancer therapy?

Autor: Michl, Patrick
Předmět:
Zdroj: Gut; Jun2012, Vol. 61 Issue 6, p790-791, 2p
Abstrakt: The article provides information related to inhibition of cathepsin in cancer therapy. It is mentioned that cathepsin B expressed in pancreatic cancer cells and acts in both intracellular and extra cellular environment. Cathepsin B degrades collagens and enhances tumor cell migration. It is discussed that inhibition of cathepsin in tumor cells in the improvement of prognosis of pancreatic cancer.
Databáze: Complementary Index