Toxic effects of chlorinated cake flour in rats.

Autor: Cunningham, H. M., Lawrence, G. A., Tryphonas, L.
Zdroj: Journal of Toxicology & Environmental Health; May1977, Vol. 2 Issue 5, p1161-1171, 11p
Abstrakt: Four experiments were conducted using weanling Wistar rats to determine whether chlorinated cake flour or its constituents were toxic. Levels of 0.2 and 1.0% chlorine added to unbleached cake flour significantly (p <0.01) reduced growth rate by 20.7 and 85.2% and increased liver weight relative to body weight by 16.7 and 25.3%, respectively. Lipids extracted from flour chlorinated at the same levels had similar effects. Rat chow diets containing 0.2 and 0.6% chlorine in the form of chlorinated wheat gluten reduced growth rate and increased liver weight as a percentage of body weight. A rat chow diet containing 0.2% chlorine as chlorinated flour lipids increased absolute liver weight by 40%, kidney by 20%, and heart by 10% compared to pair‐fed controls. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index