Comparison of Risk Prediction Using the CKD-EPI Equation and the MDRD Study Equation for Estimated Glomerular Filtration Rate.

Autor: Matsushita, Kunihiro, Mahmoodi, Bakhtawar K., Woodward, Mark, Emberson, Jonathan R., Jafar, Tazeen H., Sun Ha Jee, Polkinghorne, Kevan R., Shankar, Anoop, Smith, David H., Tonelli, Marcello, Warnock, David G., Chi-Pang Wen, Coresh, Josef, Gansevoort, Ron T., Hemmelgarn, Brenda R., Levey, Andrew S.
Předmět:
Zdroj: JAMA: Journal of the American Medical Association; 5/9/2012, Vol. 307 Issue 18, p1941-1951, 11p, 3 Charts, 3 Graphs
Abstrakt: The article discusses a study of the risk implications of estimated glomerular filtration rate (GFR) using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation as compared with the Modification of Diet in Renal Disease (MDRD) Study equation, in populations with a broad range of demographic and clinical characteristics. The researchers performed a meta-analysis of data from 1.1 million adults between March 2011 and March 2012 and computed the estimated GFR from serum creatinine standardized to isotope dilution mass spectrometry. They found that mean estimated GRF was greater when calculated using the CKD-EPI equation than by the MDRD Study equation.
Databáze: Complementary Index