Accumulation of K Ions in the Perinodal Space as a Factor Regulating the Functional State of Myelinated Nerve Fibers.

Autor: Katalymov, L., Sotnikov, O., Shurekov, V.
Předmět:
Zdroj: Neuroscience & Behavioral Physiology; May2012, Vol. 42 Issue 4, p401-407, 7p
Abstrakt: Experimental studies on intact nodes of Ranvier in isolated nerve fibers led to the conclusion that the accumulation of K ions released into the perinodal space during excitation performs a series of important functions: it decreases K release from the axoplasm, induces prolonged post-spike depolarization and its associated exaltation phase, underlies repeated and rhythmic activity, activates the electrogenic membrane Na,K-pump, and determines the generation of the prolonged component of post-tetanic hyperpolarization, which is an additional factor responsible for reabsorption of potassium ions into the cytoplasm of nerve fibers, etc. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index