| Autor: |
Dormoy, A., Froelich, N., Parissiadis, A., Cazenave, J.-P., Tongio, M.M. |
| Předmět: |
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| Zdroj: |
Tissue Antigens; Jul2002, Vol. 60 Issue 1, p88, 3p |
| Abstrakt: |
A second HLA-A[sup *]68 null allele, HLA-A[sup *]6818N, was identified in our laboratory after discrepant results were obtained between class I serological and molecular typing in a male patient suffering from narcolepsy. HLA-A[sup *]6818 N displays a sequence identical to that of the HLAA[sup *]6802 allele, except in exon 2 where 20 nucleotides inserted at codon position 48 are a repeat of the 20 preceding nucleotides. This duplication creates a shift of the reading frame, which leads to a premature non-sense codon at position 59 of the null allele. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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