| Autor: |
Kumar, Pawan, Jain, S. K., Soni, Pranay, Bodakhe, Kiran S., Namdeo, K. P., Bodakhe, Surendra H. |
| Předmět: |
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| Zdroj: |
International Journal of Pharmacology & Biological Sciences; Apr2012, Vol. 6 Issue 1, p17-23, 7p |
| Abstrakt: |
Diospyros peregrina, commonly known as Kalatendu, is widely used in different parts of India for the treatment of diabetes mellitus. The present study was designed to evaluate the antihyperglycemic effect of an methanolic extract of Diospyros peregrina leaves (DPLE) in alloxan diabetic rats. Hyperglycemia was induced by single intravenous injection of alloxan (70mg/kg body weight). The extract was administered orally at a dose of 100, 200 and 400 mg/kg body weight, to normal and alloxan diabetic rats. Significant reduction in glucose was observed in alloxan diabetic rats. The studies indicate that the DPLE exhibited statistically significant antihyperglycemic activities in glucose tolerance test and alloxan induced diabetic rats. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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