Abstrakt: |
Cyclic AMP, cyclic GMP, and histamine concentrations were determined in skin, lung, and peritoneal cells of mice, untreated, sham-treated, and treated, in vivo (1 W/cm2, 100 and 200 s), mice killed and samples taken 2-120 min after exposure. Similar experiments, also with liver, were performed with focused-beam exposures (2-MHz continuous wave, 8.4 W/cm2, 2 × 100 s; 10 W/cm2, 12 s) of areas of the mouse. In addition, wide-beam exposures, in vitro, of the peritoneal cells and human amniotic cells were included. In all of the work, no significant effect of the exposures was observed in comparison with the controls. Furthermore the percent of dead peritoneal and amniotic cells present was not affected by the exposures. These results may depend on maintenance of the integrity of the cell membranes during the exposures, in spite of the damage to other cell structures. [Research supported by the National Institute of General Medical Sciences, Grant No. GM 22684.] [ABSTRACT FROM AUTHOR] |