| Autor: |
Korfage, J.A.M., Wang, Jeffrey, Lie, S.H.J.T.J., Langenbach, Geerling E.J. |
| Zdroj: |
Muscle & Nerve; May2012, Vol. 45 Issue 5, p684-691, 8p |
| Abstrakt: |
Introduction: Muscles can adapt their fiber properties to accommodate to new conditions. We investigated the extent to which a decrease in muscle activation can cause an adaptation of fiber properties in synergistic and antagonistic jaw muscles. Methods: Three months after the injection of botulinum toxin type A in one masseter (anterior or posterior) muscle changes in fiber type composition and fiber cross-sectional areas in jaw muscles were studied at the microscopic level. Results: The injected masseter showed a steep increase in myosin type IIX fibers, whereas fast fibers decreased by about 50% in size. Depending on the injection site, both synergistic and antagonistic muscles showed a significant increase in the size of their fast IIA fibers, sometimes combined with an increased number of IIX fibers. Conclusion: Silencing the activity in the masseter not only causes changes in the fibers of the injected muscle but also leads to changes in other jaw muscles. Muscle Nerve, 2012 [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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