Mössbauer studies of hemoglobin in erythrocytes exposed to neutron radiation.

Autor: Niemiec, Katarzyna, Kaczmarska, Magdalena, Buczkowski, Mateusz, Fornal, Maria, Pohorecki, Władysław, Matlak, Krzysztof, Korecki, Józef, Grodzicki, Tomasz, Burda, Kvetoslava
Předmět:
Zdroj: Hyperfine Interactions; 2012, Vol. 206 Issue 1-3, p95-100, 6p
Abstrakt: We studied radiation effects on the stability of various states of hemoglobin (Hb) in red blood cells (RBC) irradiated with a very low dose of neutron rays, 50 μGy. We investigated RBCs isolated from blood of healthy donors. Mössbauer spectroscopy was applied to monitor different forms of Hb. Our results show, for the first time, that oxyhemoglobin (OxyHb) and deoxyhemoglobin (DeoxyHb) are two Hb forms sensitive to such a low neutron radiation. Both Hbs change into a new Hb form (Hb). Additionally, OxyHb transfers into HbOH/HO, which under our experimental conditions is resistant to the action of neutron rays. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index