| Autor: |
Russell, Alison R. Bedford |
| Zdroj: |
Infant; Mar2012, Vol. 8 Issue 2, p54-58, 5p |
| Abstrakt: |
When neonatal sepsis or necrotising enterocolitis is accompanied by neutropenia, mortality is high. The haemopoietic growth factors rhG-CSF (recombinant human granulocyte-colony stimulating factor) and rhGM-CSF (recombinant human granulocyte macrophage-colony stimulating factor) have been investigated for their ability to enhance neutrophil numbers and function. Evidence to date does not support the routine use of rhG-CSF or rhGM-CSF for either prophylaxis or treatment of newborn sepsis, but use in preterm, neutropenic and septic babies <1500g may be of benefit and could be considered in extreme situations, after consultation with parents. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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