| Autor: |
Wenke, G., Brunnemann, K., Hoffmann, D., Bhide, S. |
| Zdroj: |
Journal of Cancer Research & Clinical Oncology; 1984, Vol. 108 Issue 1, p110-113, 4p |
| Abstrakt: |
Betel quid chewing is strongly associated with cancer of the oral cavity, especially when tobacco is added to the quid. It is our working hypothesis that, during chewing, Areca-derived N-nitrosamines are formed and, in the presence of tobacco, Nicotiana-specific N-nitrosamines are formed as well and further that these agents may contribute to the high risk of oral cancer in betel-quid chewers. This preliminary report presents our finding of N-nitrosoguvacoline in the saliva of betel-quid chewers (2.2-350 ppb). When the quid contains tobacco, the tobacco-specific N-nitrosamines, N′-nitrosonornicotine (1.2-38.3 ppb), N′-nitrosoanatabine (3.2-39.5 ppb), and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (1.0-2.3 ppb) are also found in the saliva. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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