| Autor: |
Skinnider, L., Maksymiuk, W., McAskill, J |
| Zdroj: |
Journal of Cancer Research & Clinical Oncology; 1983, Vol. 105 Issue 1, p103-105, 3p |
| Abstrakt: |
Discrete pleomorphic colonies were cultured from a lymph node of a patient with Hodgkin's disease using phorbol myristate acetate in semi-solid media. A mean of 216 colonies were counted after 10 days incubation. No colonies were noted after similar incubation with pokeweed mitogen or lymphocyte conditioned medium. A gradation in morphology from small lymphoid cells to giant multinucleated cells was noted. The majority (80%) of the cultured cells bore T lymphoid suface markers. The use of phorbol myristate acetate as a stimulant for colony growth of cells from the lymph nodes of Hodgkin's disease patients would appear to be of value. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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