Abstrakt: |
We used a 1024 × 1024 pixel, 15-μm, 16-bitencoding, multi-pin-phase charge-coupled device (CCD) to obtain images of the normal human retinal nerve fiber layer. This device, which operates at room temperature, offers significantly better signal-to-noise ratio, linearity, and dynamic range than do photographic film, video imaging techniques, or commercially available CCDs. We demonstrate the use of a nonlinear digital filter, together with filter windows, that enhances fine detail of NFL striations, while suppressing noise, in limited areas of the CCD images. High-sensitivity imaging of this type, together with appropriate digital processing, may prove useful in diagnosing and following nerve-fiber-layer damage due to glaucoma. [ABSTRACT FROM AUTHOR] |