Ectopic pairing of chromosome regions containing chemically similar DNA.

Autor: Barr, H., Ellison, John
Zdroj: Chromosoma; 1972, Vol. 39 Issue 1, p53-61, 9p
Abstrakt: Using genetically controlled stocks of Drosophila melanogaster we have compared the frequency of ectopic pairing in a line showing intense quinacrine fluorescence at two sites (81F and 83E) on chromosome 3 with one showing such fluorescence at only one of these sites (81F). The frequency of ectopic pairing is an order of magnitude greater in cells from the line showing intense fluorescence in both regions than in the line showing it in only one. These data indicate that ectopic pairing is dependent upon properties of discrete chromosome regions as small as individual bands. Since A: T-rich chromatin is known to fluoresce intensely after quinacrine staining, these data further suggest that ectopic pairing is dependent on similarities of the DNA of the discrete chromosome regions involved. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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