Single episode of major depressive disorder.

Autor: Cassano, Giovanni, Akiskal, Hagop, Savino, Mario, Soriani, Adalgisa, Musetti, Laura, Perugi, Giulio
Zdroj: European Archives of Psychiatry & Clinical Neuroscience; 1993, Vol. 242 Issue 6, p373-380, 8p
Abstrakt: Of 687 consecutive inpatients and outpatients with primary major depressive illness, 213 (31%) were categorized as single episode (SE) by DSM-III-R criteria. Systematic evaluation of familial, sociodemographic, temperamental and symptomatological characteristics permitted the nearly equal division of SE into two categories: a. early-onset (<45 years) 'first episode' superimposed on either depressive or hyperthymic temperaments (against a bipolar and unipolar familial background), more severe depression, higher rates of suicide attempts, greater anxiety-somatization and psychotic tendencies, and with the potential for recurrence; b. late-onset (≥45 years) isolated episode (against an unipolar familial background) with greater life stressors, pursuing a protracted course with less likelihood of recurrence. In most other respects, early-onset SE was intermediate between recurrent major depression and lateonset SE. The implications of these findings for the now largely abandoned category of 'involutional melancholia' are discussed. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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