| Autor: |
Wright, J., Hobson, J., Wiggs, B., Hogg, J. |
| Zdroj: |
Lung; 1988, Vol. 166 Issue 1, p75-83, 9p |
| Abstrakt: |
This study compares the inflammatory cell types in the alveolar airspace, peripheral airways, and bronchoalveolar lavage fluid of 65 human lung specimens removed surgically. The data show that the cellular population in the airway tissue is composed of approximately 2-4% neutrophils, and 96-98% mononuclear inflammatory cells. This contrasts with the airway lumen, which contains approximately 5-14% neutrophils, while the alveolar airspace contains 3%, and the lavage fluid contains 4% neutrophils. There is a significant correlation between the percentage of PMN in the walls of the membranous and respiratory bronchioles, as well as between the walls and lumens of respiratory and membranous bronchioles. We conclude that: Various workers have suggested that analysis of the cell types present in bronchopulmonary lavage can be used as a therapeutic index, or as a diagnostic test. Our data suggest that lavage does indeed sample the lower airways and alveolar spaces, and that such usage may well be justified. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Full text from SpringerLink