| Autor: |
Cecchi, G., Lombardi, V., Menchetti, G. |
| Zdroj: |
Pflügers Archiv: European Journal of Physiology; 1984, Vol. 401 Issue 4, p396-401, 6p |
| Abstrakt: |
The time course of the contractile process was investigated in the presence of AR-L 115BS, a twitch potentiator which is thought to increase the rate of the Ca binding by troponin and to improve the Ca mobilization from the sarcoplasmic reticulum. AR-L 115BS increased markedly the rate of development of the force-velocity ( T-V) relation and of the isometric tetanic tension. The effect on the rate of development of the T-V relation was however substantially more intense than that on the speed of rise of tetanic tension, thus reducing considerably the isometric tension level at which the T-V relation attained its final characteristics. The velocity of shortening under zero load and the degree of curvature of the T-V relation were not affected by AR-L 115BS. These findings support the view that the development of the T-V relation and the rise of the isometric tetanic tension measure the time course of two different processes. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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