Effect of corticosterone and triiodothyronine on (Na+K)-adenosine triphosphatase activity in rat submandibular gland.

Autor: Bartolomei, Marisa, Klein, Laura, Hsiao, Paul, Lo, Chu
Zdroj: Pflügers Archiv: European Journal of Physiology; 1983, Vol. 399 Issue 4, p255-258, 4p
Abstrakt: The present study concerns the effect of glucocorticoids and triiodothyronine (T) on rat salivary (Na+K)-adenosine triphosphatase (NaK-ATPase). The results indicate that corticosterone increases submandibular gland NaK-ATPase activity with a single dose of hormone and with two daily doses on three successive days. Multiple injections of dexamethasone also increases submandibular and sublingual gland NaK-ATPase activity. The effect of glucocorticoids on salivary NaK-ATPase is selective since Mg-ATPase shows no significant differences under different steroidal states. We subsequently investigate the possibility of interaction between the effects of corticosterone and triiodothyronine on submandibular gland NaK-ATPase activity. Our studies indicate that each of these hormones increases NaK-ATPase activity in the absence of the other. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index