Contribution of long chain fatty acids to the energy supply of the rat kidney cortex.

Autor: Bertermann, H., Gronow, G., Schirmer, A., Weiss, Ch.
Zdroj: Pflügers Archiv: European Journal of Physiology; 1975, Vol. 356 Issue 1, p9-17, 9p
Abstrakt: Tubular fragments from rat kidney cortex were isolated by collagenase and suspended in an incubation medium containing a combination of several renal substrates. Substrate concentrations were in the physiological range. O uptake, total CO production, and theCO production from U-C-labeled palmitate and oleate were measured. During the first minutes of incubation the CO production from palmitate and oleate was 10.5% or 6.3%, respectively, of the total CO produced. The RQ was 0.897. A subsequent decrease of the total CO production at a constant uptake of oxygen indicated a rising contribution of fatty acids to the fuel of respiration. The renal preference for substrates other than longchain fatty acids is discussed. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index