| Autor: |
Volger, E., Schmid-Schönbein, H., Gosen, J., Klose, H., Kline, K. |
| Zdroj: |
Pflügers Archiv: European Journal of Physiology; 1975, Vol. 354 Issue 4, p319-337, 19p |
| Abstrakt: |
Employing both microscopic and photometric methods the rheology of pathological red cell aggregation was studied in model experiments. Suspensions of washed human red blood cells in dextran solutions containing rising concentrations of dextrans (M.W. 40000, 70000, 110000, 250000, 500000) were used. At low concentrations (<500 mg-%) of high molecular weight dextrans (>70000)red cell suspensions formed aggregates similar to the ones found in normal human blood. At higher concentrations, the aggregates were similar to those observed in pathological human blood. The aggregates were studied under the condition of stasis, slow flow and at shear rate of their hydrodynamic dispersion. Besides, the flow behavior of the dispersed cells at high shear rates was studied. We found: Most of the aggregation kinetics recorded by photometry and microscopy evaded detection by viscometry. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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