| Autor: |
Reiswig, J., Frazer, G., Inpanbutr, N. |
| Zdroj: |
Histochemistry & Cell Biology; 1995, Vol. 104 Issue 2, p169-174, 6p |
| Abstrakt: |
Calbindin-D (CaBP) is a vitamin D-dependent, calcium binding protein first identified in the cytoplasm of the intestinal epithelial cell. Using biotin-streptavidin immunohistochemistry, CaBP was localized to the maternal caruncular epithelium, fetal chorionic epithelium, and trophoblastic binucleated cells of the bovine placenta. Within the maternal epithelium the intensity of staining increases from second trimester pregnancies to term pregnancies, indicating a higher intracellular concentration of CaBP in the epithelium at term. Luminal and glandular epithelium of the non-caruncular endometrium also stained positively for CaBP in all stages of pregnancy observed. No CaBP was identified within the stroma or myometrium of the pregnant cow uterus. The increased level of CaBP in the caruncular epithelium during the last trimester is hypothesized to be in response to the rising demand for calcium to aid in the mineralization of the fetal skeleton. CaBP may play a role in enhancing calcium transport across the placenta in cattle. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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