Development of velvet coat ( Ve/Ve), another early lethal mutation in the house mouse.

Autor: Granholm, Nels, Stevens, Leroy, Theiler, Karl
Zdroj: Anatomy & Embryology; 1979, Vol. 157 Issue 2, p237-242, 6p
Abstrakt: A new semidominant mutation in the house mouse, velvet coat ( Ve), is described. Ve homozygotes, recognizable on day 5 of gestation by their deficiency of ectodermal cells, never produce mesoderm and are resorbed by days 9-10. Primary Ve action may occur during the formation of the blastocyst or during determination and differentiation of the inner cell mass, or both. Accordingly, Ve/Ve embryos may provide a useful model for investigating primary gene action during blastocyst formation and subsequent differentiation. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index