| Autor: |
Madhavan, Kornath, Madhavan, Mekkara |
| Zdroj: |
Roux's Archives of Developmental Biology; 1995, Vol. 204 Issue 5, p330-335, 6p |
| Abstrakt: |
The Drosophila homolog of the vertebrate EGF receptor (DER) gene is encoded by the torpedo (top) locus. We examined the role of top in the development and differentiation of the integument of the adult abdomen of Drosophila, by analysing these processes in transheterozygotes of two top alleles. The mutation, when compared to the wild type, affected mitosis, spreading and differentiation of adult epidermal cells derived from the various histoblast and spiracular nests. Our observations indicate that the need for wild-type top gene product becomes critical after pupation, and the requirement continues throughout the rest of adult development for the normal morphogenesis of the abdominal integument and spiracles. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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